GW501516 is a PPAR-delta agonist. Peroxisome proliferator activated receptors are nuclear receptors regulating gene transcription around fuel use, and the delta subtype in particular around fatty acid oxidation in skeletal muscle. It is almost universally listed alongside SARMs and is not one: SARMs act on the androgen receptor and cardarine has no androgen receptor activity whatsoever. The grouping is a retail convention rather than a pharmacological one. Development was halted by GSK after long-term rodent carcinogenicity findings, a fact worth knowing and one that listings rarely mention.
How Cardarine compares
Against actual SARMs such as ostarine or RAD-140: entirely different receptor family, no androgen receptor involvement at all. Against stimulant fat loss compounds: cardarine acts on gene transcription rather than on adrenergic signalling, so its mechanism has nothing in common with them either. It is genuinely its own category and is filed under the wrong one nearly everywhere.
| Class | PPAR-delta agonist |
| Also known as | GW-501516, GW1516 |
| Presentation | Oral liquid or capsule. |
| Pharmacokinetics | Approximately 16 to 24 hours. |
| Storage | Cool, dry, dark. |
Quanta Pharma Cardarine 10mgout of stock£30
Availability checked 2026-09-08. The product page carries live stock.